Colossians is a unique letter in the New Testament because it was the only city Paul never visited, but to which he had personally written. Some the same is true of Rome and while he may not have been there by 57AD upon the writting of his letter to them, we know that he did in fact meet them since he was under house arrest in Rome for two years beginning in 60AD.
Paul had led a man named Epaphras to Christ while ministering in Ephesus. This man returned to his home town of Colossae, evangelized it and established the church there which probably met in the house of Philemon.
Years later when Paul in again in prison, Epaphras came to visit Paul with concerns over the hellenizing influence of differenbt forms of mysticism and Judaism was having upon their doctrine and solidity in Christ. It was in response to this news that Paul wrote this wonderful and redemptive letter to the saints in Colossae.
In the first chapter Paul addresses the sincerity of their faith and their genuine love for the saints. Because this was true, Paul knew their wavering in doctrine was not purposeful and so he prayed that they might have a walk worthy of God and live lives fully pleasinbg to Him BY being filled with the knowledge of His will!
Such offers us some clarity regarding how to pray for genuine believers who have wondered into false doctrine and need to be re-established and fortefied in sound and solid doctrine.
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